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SELECT 
  b.variant_name, 
  a.*, 
  IF(
    shared_option_variants.variant_id IS NOT NULL, 
    shared_option_variants.modifier, 
    a.modifier
  ) as modifier, 
  IF(
    shared_option_variants.variant_id IS NOT NULL, 
    shared_option_variants.modifier_type, 
    a.modifier_type
  ) as modifier_type 
FROM 
  cscart_product_option_variants AS a 
  LEFT JOIN cscart_product_option_variants_descriptions AS b ON b.variant_id = a.variant_id 
  AND b.lang_code = 'en' 
  LEFT JOIN cscart_ult_product_option_variants shared_option_variants ON shared_option_variants.variant_id = a.variant_id 
  AND shared_option_variants.company_id = 1 
WHERE 
  1 
  AND a.option_id IN (
    100408, 100407, 100406, 100405, 100404, 
    100403, 100402, 100401, 100400, 100389, 
    100388, 100387, 100386, 100385, 100384, 
    100383, 100382, 100381, 100380, 100379
  ) 
  AND a.status = 'A' 
ORDER BY 
  a.position, 
  a.variant_id

Query time 0.00118

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE	a	range	status,option_id,option_id_2	option_id	6		40	Using index condition; Using filesort
1	SIMPLE	b	eq_ref	PRIMARY	PRIMARY	9	toolboxdigitalshop_dev.a.variant_id,const	1	Using where
1	SIMPLE	shared_option_variants	eq_ref	PRIMARY,company_id	PRIMARY	7	toolboxdigitalshop_dev.a.variant_id,const	1

Result

variant_name	variant_id	option_id	position	modifier	modifier_type	weight_modifier_type	point_modifier_type	status
MP3	201294	100379	1	0.000	A	A	A	A
MP3	201296	100380	1	0.000	A	A	A	A
MP3	201298	100381	1	0.000	A	A	A	A
MP3	201300	100382	1	0.000	A	A	A	A
MP3	201302	100383	1	0.000	A	A	A	A
MP3	201304	100384	1	0.000	A	A	A	A
MP3	201306	100385	1	0.000	A	A	A	A
MP3	201308	100386	1	0.000	A	A	A	A
MP3	201310	100387	1	0.000	A	A	A	A
MP3	201312	100388	1	0.000	A	A	A	A
MP3	201314	100389	1	0.000	A	A	A	A
MP3	201336	100400	1	0.000	A	A	A	A
MP3	201338	100401	1	0.000	A	A	A	A
MP3	201340	100402	1	0.000	A	A	A	A
MP3	201342	100403	1	0.000	A	A	A	A
MP3	201344	100404	1	0.000	A	A	A	A
MP3	201346	100405	1	0.000	A	A	A	A
MP3	201348	100406	1	0.000	A	A	A	A
MP3	201350	100407	1	0.000	A	A	A	A
MP3	201352	100408	1	0.000	A	A	A	A
WAV	201295	100379	2	0.300	A	A	A	A
WAV	201297	100380	2	0.300	A	A	A	A
WAV	201299	100381	2	0.300	A	A	A	A
WAV	201301	100382	2	0.300	A	A	A	A
WAV	201303	100383	2	0.300	A	A	A	A
WAV	201305	100384	2	0.300	A	A	A	A
WAV	201307	100385	2	0.300	A	A	A	A
WAV	201309	100386	2	0.300	A	A	A	A
WAV	201311	100387	2	0.300	A	A	A	A
WAV	201313	100388	2	0.300	A	A	A	A
WAV	201315	100389	2	0.300	A	A	A	A
WAV	201337	100400	2	0.300	A	A	A	A
WAV	201339	100401	2	0.300	A	A	A	A
WAV	201341	100402	2	0.300	A	A	A	A
WAV	201343	100403	2	0.300	A	A	A	A
WAV	201345	100404	2	0.300	A	A	A	A
WAV	201347	100405	2	0.300	A	A	A	A
WAV	201349	100406	2	0.300	A	A	A	A
WAV	201351	100407	2	0.300	A	A	A	A
WAV	201353	100408	2	0.300	A	A	A	A