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SELECT 
  cscart_ult_product_descriptions.product_id, 
  cscart_ult_product_descriptions.short_description, 
  IF(
    cscart_ult_product_descriptions.short_description = "", 
    cscart_ult_product_descriptions.full_description, 
    ""
  ) AS full_description, 
  cscart_ult_product_descriptions.meta_keywords, 
  cscart_ult_product_descriptions.meta_description, 
  cscart_ult_product_descriptions.search_words, 
  cscart_ult_product_descriptions.promo_text 
FROM 
  cscart_ult_product_descriptions 
WHERE 
  cscart_ult_product_descriptions.product_id IN (
    42450, 42449, 42448, 42447, 42446, 42445, 
    42444, 42443, 42442, 42441, 42440, 
    42439, 42438, 42437, 42436, 42435, 
    42433, 42271, 42270, 42269
  ) 
  AND cscart_ult_product_descriptions.company_id = 1 
  AND cscart_ult_product_descriptions.lang_code = 'en'

Query time 0.00021

Explain
id	select_type	table	type	possible_keys	key	key_len	ref	rows	Extra
1	SIMPLE	cscart_ult_product_descriptions	ALL	PRIMARY,product_id,company_id				1	Using where